SLAMF6 monoclonal antibody, clone 8F1C2
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human SLAMF6.
Immunogen
Recombinant protein corresponding to amino acids 22-226 of human SLAMF6.
Host
Mouse
Theoretical MW (kDa)
37.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: SLAMF6-hIgGFc transfected HEK293 cell lysates with SLAMF6 monoclonal antibody, clone 8F1C2 (Cat # MAB21336).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with SLAMF6 monoclonal antibody, clone 8F1C2 (Cat # MAB21336). -
Gene Info — SLAMF6
Entrez GeneID
114836Protein Accession#
Q96DU3Gene Name
SLAMF6
Gene Alias
KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000
Gene Description
SLAM family member 6
Omim ID
606446Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. [provided by RefSeq
Other Designations
NTBA receptor|OTTHUMP00000024348|activating NK receptor|natural killer-, T- and B-cell antigen
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