SLAMF6 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SLAMF6 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SLAMF6 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SLAMF6 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SLAMF6
Entrez GeneID
114836GeneBank Accession#
SLAMF6Gene Name
SLAMF6
Gene Alias
KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000
Gene Description
SLAM family member 6
Omim ID
606446Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. [provided by RefSeq
Other Designations
NTBA receptor|OTTHUMP00000024348|activating NK receptor|natural killer-, T- and B-cell antigen
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Interactome
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Disease
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