TNFRSF4 monoclonal antibody, clone 2D1B8
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More Files
- More Functions
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TNFRSF4 monoclonal antibody, clone 2D1B8 (Cat # MAB17977).
Flow Cytometry
Flow cytometric analysis of HeLa cells with TNFRSF4 monoclonal antibody, clone 2D1B8 (Cat # MAB17977) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human TNFRSF4.
Immunogen
Recombinant protein corresponding to amino acids 29-214 of human TNFRSF4.
Host
Mouse
Theoretical MW (kDa)
29.3
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TNFRSF4 monoclonal antibody, clone 2D1B8 (Cat # MAB17977).Flow Cytometry
Flow cytometric analysis of HeLa cells with TNFRSF4 monoclonal antibody, clone 2D1B8 (Cat # MAB17977) (Green). Red: Negative Control. -
Gene Info — TNFRSF4
Entrez GeneID
7293Protein Accession#
P43489Gene Name
TNFRSF4
Gene Alias
ACT35, CD134, OX40, TXGP1L
Gene Description
tumor necrosis factor receptor superfamily, member 4
Omim ID
600315Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq
Other Designations
ATC35 antigen|CD134 antigen|OTTHUMP00000001522|OX40 antigen|OX40 cell surface antigen|OX40 homologue|lymphoid activation antigene ACT35|tax-transcriptionally activated glycoprotein 1 receptor
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Interactome
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Pathway
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Disease
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