FBXL10 monoclonal antibody, clone 6F6G11
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human FBXL10.
Immunogen
Recombinant protein corresponding to amino acid 457-555 of human FBXL10 from E. coli.
Host
Mouse
Theoretical MW (kDa)
152.6kDa
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using FBXL10 monoclonal antibody against A549 cell.Western Blot (Transfected lysate)
Western Blot analysis of (1) HEK293 cells, (2) FBXL10-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of FBXL10 monoclonal antibody, clone 6F6G11.Flow Cytometry
Flow cytometric analysis of HeLa cells with FBXL10 monoclonal antibody (green) and negative control (red). -
Gene Info — FBXL10
Entrez GeneID
84678Gene Name
FBXL10
Gene Alias
CXXC2, Fbl10, JHDM1B, KDM2B, PCCX2
Gene Description
F-box and leucine-rich repeat protein 10
Omim ID
609078Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein|jumonji C domain-containing histone demethylase 1B|protein containing CXXC domain 2
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Interactome
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Disease
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