MADCAM1 monoclonal antibody, clone 314G8
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with MADCAM1 monoclonal antibody, clone 314G8 (Cat # MAB12575) at 10 ug/mL working concentration.
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Specification
Product Description
Mouse monoclonal antibody raised against human MADCAM1.
Immunogen
Recombinant protein corresponding to human MADCAM1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1
Recommend Usage
ELISA
Flow Cytometry (1:10-1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4.
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with MADCAM1 monoclonal antibody, clone 314G8 (Cat # MAB12575) at 10 ug/mL working concentration.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — MADCAM1
Entrez GeneID
8174Gene Name
MADCAM1
Gene Alias
MACAM1
Gene Description
mucosal vascular addressin cell adhesion molecule 1
Omim ID
102670Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
mucosal addressin cell adhesion molecule-1
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Interactome
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Pathway
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Disease
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