MADCAM1 recombinant monoclonal antibody, clone 12B5
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MADCAM1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human MADCAM1.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing PC3 cells stained with MADCAM1 recombinant monoclonal antibody, clone 12B5 (red line) at 1:100. -
Gene Info — MADCAM1
Entrez GeneID
8174Protein Accession#
Q13477Gene Name
MADCAM1
Gene Alias
MACAM1
Gene Description
mucosal vascular addressin cell adhesion molecule 1
Omim ID
102670Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
mucosal addressin cell adhesion molecule-1
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Interactome
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Pathway
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Disease
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