MTPN purified MaxPab mouse polyclonal antibody (B03P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MTPN protein.
Immunogen
MTPN (NP_665807.1, 1 a.a. ~ 118 a.a) full-length human protein.
Sequence
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MTPN MaxPab polyclonal antibody. Western Blot analysis of MTPN expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of MTPN expression in transfected 293T cell line (H00136319-T04) by MTPN MaxPab polyclonal antibody.
Lane 1: MTPN transfected lysate(12.90 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MTPN on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — MTPN
Entrez GeneID
136319GeneBank Accession#
NM_145808Protein Accession#
NP_665807.1Gene Name
MTPN
Gene Alias
FLJ31098, FLJ99857, GCDP, V-1
Gene Description
myotrophin
Omim ID
606484Gene Ontology
HyperlinkGene Summary
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq
Other Designations
granule cell differentiation protein
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Interactome
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