MTPN 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
MTPN transfected lysate.
Western Blot
Lane 1: MTPN transfected lysate ( 12.9 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pV5-MTPN full-length
Host
Human
Theoretical MW (kDa)
12.9
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MTPN antibody (H00136319-B03P) by Western Blots.
SDS-PAGE Gel
MTPN transfected lysate.
Western Blot
Lane 1: MTPN transfected lysate ( 12.9 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MTPN
Entrez GeneID
136319GeneBank Accession#
NM_145808Protein Accession#
NP_665807.1Gene Name
MTPN
Gene Alias
FLJ31098, FLJ99857, GCDP, V-1
Gene Description
myotrophin
Omim ID
606484Gene Ontology
HyperlinkGene Summary
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq
Other Designations
granule cell differentiation protein
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