PUS1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PUS1 protein.
Immunogen
PUS1 (AAH02901.1, 1 a.a. ~ 399 a.a) full-length human protein.
Sequence
MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PUS1 expression in transfected 293T cell line (H00080324-T01) by PUS1 MaxPab polyclonal antibody.
Lane 1: PUS1 transfected lysate(44.00 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PUS1
Entrez GeneID
80324GeneBank Accession#
BC002901.2Protein Accession#
AAH02901.1Gene Name
PUS1
Gene Alias
MGC11268, MLASA
Gene Description
pseudouridylate synthase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants
Other Designations
pseudouridine synthase 1
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