ARHGEF18 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ARHGEF18 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSQGMQRMHLETLQQVDKWPLCGPLACSELLQLTVRSLEGWRKEVLGSIKGAGTSQGGEIHPRSSSGGERAHVKPCSAPQALVVGLGPG
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ARHGEF18
Entrez GeneID
23370GeneBank Accession#
BC008016.1Protein Accession#
AAH08016.1Gene Name
ARHGEF18
Gene Alias
KIAA0521, MGC15913, P114-RhoGEF
Gene Description
rho/rac guanine nucleotide exchange factor (GEF) 18
Gene Ontology
HyperlinkGene Summary
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
P114-RHO-GEF|Rho-specific guanine nucleotide exchange factor p114
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