MAP4K5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MAP4K5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MAP4K5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MAP4K5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MAP4K5
Entrez GeneID
11183GeneBank Accession#
MAP4K5Gene Name
MAP4K5
Gene Alias
GCKR, KHS, KHS1, MAPKKKK5
Gene Description
mitogen-activated protein kinase kinase kinase kinase 5
Omim ID
604923Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq
Other Designations
germinal center kinase-related|kinase homologous to SPS1/STE20
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Interactome
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Disease
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