TJP2 monoclonal antibody (M01), clone 4D12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TJP2.
Immunogen
TJP2 (NP_004808, 121 a.a. ~ 218 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TJP2 monoclonal antibody (M01), clone 4D12. Western Blot analysis of TJP2 expression in HepG2.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TJP2 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — TJP2
Entrez GeneID
9414GeneBank Accession#
NM_004817Protein Accession#
NP_004808Gene Name
TJP2
Gene Alias
MGC26306, X104, ZO-2, ZO2
Gene Description
tight junction protein 2 (zona occludens 2)
Gene Ontology
HyperlinkGene Summary
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM
Other Designations
Friedreich ataxia region gene X104 (tight junction protein ZO-2)|OTTHUMP00000021431|OTTHUMP00000063359
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Interactome
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Pathway
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