MAPKSP1 monoclonal antibody (M03), clone 2A4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of MAPKSP1 expression in transfected 293T cell line by MAPKSP1 monoclonal antibody (M03), clone 2A4.
Lane 1: MAPKSP1 transfected lysate(13.623 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (35.31 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAPKSP1.
Immunogen
MAPKSP1 (NP_068805, 1 a.a. ~ 87 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.31 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MAPKSP1 expression in transfected 293T cell line by MAPKSP1 monoclonal antibody (M03), clone 2A4.
Lane 1: MAPKSP1 transfected lysate(13.623 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — MAPKSP1
Entrez GeneID
8649GeneBank Accession#
NM_021970Protein Accession#
NP_068805Gene Name
MAPKSP1
Gene Alias
MAP2K1IP1, MAPBP, MP1
Gene Description
MAPK scaffold protein 1
Omim ID
603296Gene Ontology
HyperlinkGene Summary
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq
Other Designations
MEK binding partner 1|MEK partner 1|mitogen-activated protein kinase kinase 1 interacting protein 1
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Interactome
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Pathway
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