MAPKSP1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MAPKSP1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRQVVEVS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MAPKSP1
Entrez GeneID
8649GeneBank Accession#
NM_021970.2Protein Accession#
NP_068805.1Gene Name
MAPKSP1
Gene Alias
MAP2K1IP1, MAPBP, MP1
Gene Description
MAPK scaffold protein 1
Omim ID
603296Gene Ontology
HyperlinkGene Summary
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq
Other Designations
MEK binding partner 1|MEK partner 1|mitogen-activated protein kinase kinase 1 interacting protein 1
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Interactome
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Pathway
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