SMARCA2 monoclonal antibody (M06), clone 2D12
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SMARCA2 is approximately 0.1ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to SMARCA2 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (34.21 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SMARCA2.
Immunogen
SMARCA2 (NP_003061, 659 a.a. ~ 735 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (97)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.21 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SMARCA2 is approximately 0.1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SMARCA2 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — SMARCA2
Entrez GeneID
6595GeneBank Accession#
NM_003070Protein Accession#
NP_003061Gene Name
SMARCA2
Gene Alias
BAF190, BRM, FLJ36757, MGC74511, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Omim ID
600014Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq
Other Designations
OTTHUMP00000020970|OTTHUMP00000020971|SNF2-alpha|SNF2-like 2|SNF2/SWI2-like protein 2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2|global transcription activator homologous sequence|sucrose nonfermenting 2-like protein 2
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Interactome
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Disease
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