PTGDS MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PTGDS protein.
Immunogen
PTGDS (NP_000945.3, 1 a.a. ~ 190 a.a) full-length human protein.
Sequence
MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PTGDS expression in transfected 293T cell line (H00005730-T01) by PTGDS MaxPab polyclonal antibody.
Lane 1: PTGDS transfected lysate(20.9 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PTGDS
Entrez GeneID
5730GeneBank Accession#
NM_000954.5Protein Accession#
NP_000945.3Gene Name
PTGDS
Gene Alias
LPGDS, PDS, PGD2, PGDS, PGDS2
Gene Description
prostaglandin D2 synthase 21kDa (brain)
Omim ID
176803Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq
Other Designations
OTTHUMP00000022638|PGD2 synthase|beta-trace protein|glutathione-independent PGD synthase|lipocalin-type prostaglandin D synthase|prostaglandin D synthase|prostaglandin D2 synthase (21kD, brain)|prostaglandin H2 D-isomerase|prostaglandin-H2 D-isomerase
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Interactome
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Pathway
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Disease
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