PTGDS rabbit monoclonal antibody

Catalog # H00005730-K

Size

Price

Stock

Quantity

Size:100 ug x up to 3
Price: -
Stock:
made to order, 8 months
abnova-minus
abnova-plus

* The price is valid only in USA. Please select country.

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Rabbit monoclonal antibody raised against a human PTGDS peptide using ARM Technology.

    Immunogen

    A synthetic peptide of human PTGDS is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.

    Host

    Rabbit

    Library Construction

    Non-fusion antibody library from rabbit spleen (ARM Technology).

    Expression

    Overexpression vector and transfection into 293H cell line.

    Reactivity

    Human

    Purification

    Protein A

    Isotype

    IgG

    Quality Control Testing

    Antibody reactive against human PTGDS peptide by ELISA and mammalian transfected lysate by Western Blot.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

    Deliverable

    Up to three rabbit IgG clones of 100 ug each will be delivered to customer.

    Note

    1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

  • Applications

    Western Blot (Transfected lysate)

    ELISA

  • Gene Info — PTGDS

    Entrez GeneID

    5730

    GeneBank Accession#

    PTGDS

    Gene Name

    PTGDS

    Gene Alias

    LPGDS, PDS, PGD2, PGDS, PGDS2

    Gene Description

    prostaglandin D2 synthase 21kDa (brain)

    Omim ID

    176803

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq

    Other Designations

    OTTHUMP00000022638|PGD2 synthase|beta-trace protein|glutathione-independent PGD synthase|lipocalin-type prostaglandin D synthase|prostaglandin D synthase|prostaglandin D2 synthase (21kD, brain)|prostaglandin H2 D-isomerase|prostaglandin-H2 D-isomerase

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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