PTGDS 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PTGDS transfected lysate.
Western Blot
Lane 1: PTGDS transfected lysate ( 21.01 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PTGDS full-length
Host
Human
Theoretical MW (kDa)
21.01
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PTGDS antibody (H00005730-B01) by Western Blots.
SDS-PAGE Gel
PTGDS transfected lysate.
Western Blot
Lane 1: PTGDS transfected lysate ( 21.01 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PTGDS
Entrez GeneID
5730GeneBank Accession#
NM_000954.5Protein Accession#
NP_000945.3Gene Name
PTGDS
Gene Alias
LPGDS, PDS, PGD2, PGDS, PGDS2
Gene Description
prostaglandin D2 synthase 21kDa (brain)
Omim ID
176803Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq
Other Designations
OTTHUMP00000022638|PGD2 synthase|beta-trace protein|glutathione-independent PGD synthase|lipocalin-type prostaglandin D synthase|prostaglandin D synthase|prostaglandin D2 synthase (21kD, brain)|prostaglandin H2 D-isomerase|prostaglandin-H2 D-isomerase
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Interactome
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Pathway
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Disease
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