PAFAH1B3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PAFAH1B3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PAFAH1B3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PAFAH1B3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PAFAH1B3
Entrez GeneID
5050GeneBank Accession#
PAFAH1B3Gene Name
PAFAH1B3
Gene Alias
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Gene Description
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa
Omim ID
603074Gene Ontology
HyperlinkGene Summary
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD)
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Interactome
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Pathway
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