CISH purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
CISH MaxPab polyclonal antibody. Western Blot analysis of CISH expression in human spleen.
Western Blot (Transfected lysate)
Western Blot analysis of CISH expression in transfected 293T cell line (H00001154-T01) by CISH MaxPab polyclonal antibody.
Lane 1: CISH transfected lysate(28.38 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to CISH on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CISH protein.
Immunogen
CISH (NP_659508.1, 1 a.a. ~ 258 a.a) full-length human protein.
Sequence
MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CISH MaxPab polyclonal antibody. Western Blot analysis of CISH expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of CISH expression in transfected 293T cell line (H00001154-T01) by CISH MaxPab polyclonal antibody.
Lane 1: CISH transfected lysate(28.38 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to CISH on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — CISH
Entrez GeneID
1154GeneBank Accession#
NM_145071Protein Accession#
NP_659508.1Gene Name
CISH
Gene Alias
CIS, CIS-1, G18, SOCS
Gene Description
cytokine inducible SH2-containing protein
Omim ID
602441Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
cytokine-inducible SH2-containing protein|cytokine-inducible inhibitor of signaling type 1B|suppressor of cytokine signaling
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Interactome
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Pathway
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Disease
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