NAT2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NAT2 full-length
Host
Human
Theoretical MW (kDa)
32.01
Interspecies Antigen Sequence
Mouse (72); Rat (74)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NAT2 antibody (H00000010-B01) by Western Blots.
Western Blot
Lane 1: NAT2 transfected lysate ( 33.5 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
NAT2 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NAT2
Entrez GeneID
10GeneBank Accession#
BC015878.1Protein Accession#
-Gene Name
NAT2
Gene Alias
AAC2, PNAT
Gene Description
N-acetyltransferase 2 (arylamine N-acetyltransferase)
Omim ID
243400Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq
Other Designations
N-acetyltransferase 2|arylamide acetylase 2|arylamine N-acetyltransferase 2
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Interactome
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Disease
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