Anti-Cetuximab monoclonal antibody, clone 6D4-9
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Specifications
Product Description
Mouse monoclonal antibody raised against F(ab)2 fragment of Cetuximab.
Target gene is EGFR.Immunogen
F(ab)2 fragment of Cetuximab.
Host
Mouse
Specificity
This antibody is able to interfere the binding between Cetuximab and EGFR-expressing A431 cells.
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
ELISA (2 ug/mL for coating)
The optimal working dilution should be determined by the end user.Storage Buffer
In TBS, pH 8.0 (0.09% sodium azide).
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — EGFR
Entrez GeneID
1956Gene Name
EGFR
Gene Alias
ERBB, ERBB1, HER1, PIG61, mENA
Gene Description
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Other Designations
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Development of NanoLuc bridging immunoassay for detection of anti-drug antibodies.
Nath N, Flemming R, Godat B, Urh M.
Journal of Immunological Methods 2017 Jul; 450:17.
Application：Func, Human, Human serum.
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Development of NanoLuc bridging immunoassay for detection of anti-drug antibodies.
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