MXI1 monoclonal antibody (M11), clone 1B10
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MXI1 is 0.03 ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to MXI1 on U-2 OS cell. [antibody concentration 10 ug/ml]
Immunofluorescence
Immunofluorescence of monoclonal antibody to MXI1 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (45.76 KDa) .
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant MXI1.
Immunogen
MXI1 (AAH12907, 1 a.a. ~ 182 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (94)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (45.76 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MXI1 is 0.03 ng/ml as a capture antibody.ELISA
Immunofluorescence (Circulating Tumor Cell)
Immunofluorescence
Immunofluorescence of monoclonal antibody to MXI1 on U-2 OS cell. [antibody concentration 10 ug/ml]Immunofluorescence
Immunofluorescence of monoclonal antibody to MXI1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — MXI1
Entrez GeneID
4601GeneBank Accession#
BC012907Protein Accession#
AAH12907Gene Name
MXI1
Gene Alias
MAD2, MGC43220, MXD2, MXI, bHLHc11
Gene Description
MAX interactor 1
Gene Ontology
HyperlinkGene Summary
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq
Other Designations
MAX dimerization protein 2|MAX interacting protein 1|MAX-interacting protein 1|Max-related transcription factor|OTTHUMP00000020467|OTTHUMP00000020468|OTTHUMP00000020469
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Interactomes
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Diseases
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