ACADM polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.11 KDa) .
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant ACADM.
Immunogen
ACADM (NP_000007, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ACADM
Entrez GeneID
34GeneBank Accession#
NM_000016Protein Accession#
NP_000007Gene Name
ACADM
Gene Alias
ACAD1, FLJ18227, FLJ93013, FLJ99884, MCAD, MCADH
Gene Description
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
Gene Ontology
HyperlinkGene Summary
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011345|medium-chain specific acyl-CoA dehydrogenase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure.
Rennison JH, McElfresh TA, Okere IC, Patel HV, Foster AB, Patel KK, Stoll MS, Minkler PE, Fujioka H, Hoit BD, Young ME, Hoppel CL, Chandler MP.
Cardiovascular Research 2008 Mar; 79(2):331.
Application：WB, Rat, Rat heart.
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Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure.
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