AARS (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95%); Rat (95%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of AARS transfected lysate using rabbit polyclonal anti-AARS and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-AARS.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-AARS (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-AARS (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — AARS
Entrez GeneID
16Gene Name
AARS
Gene Alias
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Gene Description
alanyl-tRNA synthetase
Omim ID
601065Gene Ontology
HyperlinkGene Summary
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq
Other Designations
alanine tRNA ligase 1, cytoplasmic
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Interactome
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Pathway
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