Apoptosis is the process of programmed cell death. It is used to dispose non-needed cells by multicellular organisms. In the process of cell death, apoptosis involves series of biochemical events in a cell, including cell shrinkage, chromatin condensation, membrane blebbing, nuclear collapse and DNA fragmentation. Some of those events can be used to detect the occurrence of apoptosis.
Apoptosis plays an important role in embryonic development and many diseases such as cancer. It has become a hot research field and many detection methods have been established. Listed below are some features that can be used to detect apoptosis:
- Caspase activation
- Annexin V binding
- Mitochondrial membrane potential change
- DNA fragmentation
- Cytochrome c release
Abnova provides the research tools, including antibodies, antibodies array, proteins, chimera RNAi, ELISA and assay kits for apoptosis research.
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Antibody Product Showcase |
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Apoptosis Antibodies |  |
Apoptosis Antibody Array |
| 2560+ antibodies detecting programmed cell death in multicellular organisms. | 5 antibody arrays for apoptosis research. | ||
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Apoptosis Proteins |  |
Apoptosis Antibody Pairs |
| 900+ proteins related to apoptosis. | 220+ antibody pairs related to apoptosis. | ||
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Apoptosis Chimera RNAi |  |
Apoptosis ELISA Kits |
| 480+ Chimera RNAis for apoptosis research. | 110+ complete ELISA kits detecting programmed cell death in multicellular organisms. | ||
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Caspase Assay kits |  |
Annexin V Assay kits |
| 40+ assay kits for detect activated caspase or caspase inhibitors. | 10+ assay kit for detecting annexin v which can promotes pro-apoptotic mechanisms. | ||
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Mitochondrial Assay kits |  |
TUNEL/DNA Fragmentation Assay kits |
| 2 assay kits for detect apoptosis by mitochondrial changes. | 7 assay kits using TUNEL for detecting DNA fragmentation in apoptotic cells. | ||
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Apoptosis Marker Assay kits | ||
| 6 assay kits for measuring cathepsin family activity using fluorometric methods. | |||
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Publications |