EZH2 recombinant monoclonal antibody, clone 10H8
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human EZH2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human EZH2.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of EZH2 recombinant monoclonal antibody, clone 10H8 diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EZH2
Entrez GeneID
2146Protein Accession#
Q15910Gene Name
EZH2
Gene Alias
ENX-1, EZH1, KMT6, MGC9169
Gene Description
enhancer of zeste homolog 2 (Drosophila)
Omim ID
601573Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
enhancer of zeste 2
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Interactome
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Disease
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