EZH2 monoclonal antibody, clone 144CT2.1.1.5
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Specification
Product Description
Mouse monoclonal antibody raised against human EZH2.
Immunogen
Recombinant protein corresponding to human EZH2.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (1:10-1:50)
Immunofluorescence (1:10-1:50)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of T47D cell line lysates reacted with EZH2 monoclonal antibody (Cat # MAB12295) at 1:100-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human testis tissue reacted with EZH2 monoclonal antibody (Cat # MAB12295) at 1:10-1:50 dilution.Immunofluorescence
Immunofluorescent staining of U251 cell reacted with EZH2 monoclonal antibody (Cat # MAB12295) at 1:10-1:50 dilution. -
Gene Info — EZH2
Entrez GeneID
2146Gene Name
EZH2
Gene Alias
ENX-1, EZH1, KMT6, MGC9169
Gene Description
enhancer of zeste homolog 2 (Drosophila)
Omim ID
601573Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
enhancer of zeste 2
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Interactome
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Disease
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