COX6C recombinant monoclonal antibody, clone R06-1D9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human COX6C.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human COX6C.
Theoretical MW (kDa)
Calculated MW: 9 kDa
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: 3T3 and Lane 2: Hela lysates with COX6C recombinant monoclonal antibody, clone R06-1D9 (Cat # RAB02343).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon cancer with COX6C recombinant monoclonal antibody, clone R06-1D9 (Cat # RAB02343). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Gene Info — COX6C
Entrez GeneID
1345Protein Accession#
P09669Gene Name
COX6C
Gene Alias
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Gene Description
cytochrome c oxidase subunit VIc
Omim ID
124090Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse COX subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene COX6CP1 has been found on chromosomes 16p12. [provided by RefSeq
Other Designations
cytochrome c oxidase subunit VIc preprotein
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Interactome
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