FDFT1 recombinant monoclonal antibody, clone R08-6B1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FDFT1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human FDFT1
Theoretical MW (kDa)
Calculated MW: 48 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of FDFT1 in K562, C6, Hela lysates using human FDFT1 recombinant monoclonal antibody, clone R08-6B1 (Cat # RAB01707).Immunocytochemistry
Immunocytochemistry analysis of FDFT1(green) in Hela using human FDFT1 recombinant monoclonal antibody, clone R08-6B1 (Cat # RAB01707), and DAPI(blue).Immunoprecipitation
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Gene Info — FDFT1
Entrez GeneID
2222Protein Accession#
P37268Gene Name
FDFT1
Gene Alias
DGPT, ERG9, SQS, SS
Gene Description
farnesyl-diphosphate farnesyltransferase 1
Omim ID
184420Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq
Other Designations
FPP:FPP farnesyltransferase|presqualene-di-diphosphate synthase|squalene synthase
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Interactome
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Pathway
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Disease
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