FDFT1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FDFT1 expression in transfected 293T cell line (H00002222-T01) by FDFT1 MaxPab polyclonal antibody.
Lane 1: FDFT1 transfected lysate(45.87 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human FDFT1 protein.
Immunogen
FDFT1 (NP_004453.3, 1 a.a. ~ 417 a.a) full-length human protein.
Sequence
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FDFT1 expression in transfected 293T cell line (H00002222-T01) by FDFT1 MaxPab polyclonal antibody.
Lane 1: FDFT1 transfected lysate(45.87 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FDFT1
Entrez GeneID
2222GeneBank Accession#
NM_004462.3Protein Accession#
NP_004453.3Gene Name
FDFT1
Gene Alias
DGPT, ERG9, SQS, SS
Gene Description
farnesyl-diphosphate farnesyltransferase 1
Omim ID
184420Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq
Other Designations
FPP:FPP farnesyltransferase|presqualene-di-diphosphate synthase|squalene synthase
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Interactome
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Pathway
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Disease
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