ACACA recombinant monoclonal antibody, clone R05-3D6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of residues surrounding Ser79 of human Acetyl Coenzyme A Carboxylase.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to residues surrounding Ser79 of human Acetyl Coenzyme A Carboxylase
Theoretical MW (kDa)
Calculated MW: 266 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — ACACA
Entrez GeneID
31Protein Accession#
Q13085Gene Name
ACACA
Gene Alias
ACAC, ACC, ACC1, ACCA
Gene Description
acetyl-Coenzyme A carboxylase alpha
Omim ID
200350Gene Ontology
HyperlinkGene Summary
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
ACC-alpha|OTTHUMP00000164069|acetyl-CoA carboxylase 1|acetyl-CoA carboxylase-alpha
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