MYC recombinant monoclonal antibody, clone MYC2895R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial human MYC.
Antibody Species
Rabbit
Immunogen
Recombinant tag fusion protein corresponding to amino acids 408-439 at C-terminus of human MYC.
Sequence
AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
ELISA (For coating)
Flow Cytometry (1-2 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometric analysis of K562 cells. Goat anti-mouse IgG-CF488 (Blue) ; Isotype Control (Red). -
Gene Info — MYC
Entrez GeneID
4609Protein Accession#
P01106Gene Name
MYC
Gene Alias
bHLHe39, c-Myc
Gene Description
v-myc myelocytomatosis viral oncogene homolog (avian)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq
Other Designations
avian myelocytomatosis viral oncogene homolog|myc proto-oncogene protein|v-myc avian myelocytomatosis viral oncogene homolog
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Interactome
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Pathway
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Disease
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