GYPA recombinant monoclonal antibody, clone GYPA/1725R
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Specifications
Product Description
Rabbit recombinant monoclonal antibody raised against human GYPA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human GYPA.
Theoretical MW (kDa)
39
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human angiosarcoma with GYPA recombinant monoclonal antibody, clone GYPA/1725R (Cat # RAB00329).Immunofluorescence
Flow Cytometry
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Gene Info — GYPA
Entrez GeneID
2993Protein Accession#
P02724Gene Name
GYPA
Gene Alias
CD235a, GPA, GPErik, GPSAT, GpMiIII, HGpMiIII, HGpMiV, HGpMiX, HGpMiXI, HGpSta(C), MN, MNS
Gene Description
glycophorin A (MNS blood group)
Gene Ontology
HyperlinkGene Summary
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq
Other Designations
Mi.V glycoprotein (24 AA)|erythroid-lineage-specific membrane sialoglycoprotein|glycophorin A|glycophorin A (MN blood group)|glycophorin A MNS blood group|glycophorin A, GPA|glycophorin Erik|glycophorin MiI|glycophorin MiIII|glycophorin MiV|glycophorin Mi
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Glycophorin A expression in malignant hematopoiesis.
Liszka K, Majdic O, Bettelheim P, Knapp W.
American Journal of Hematology 1983 Nov; 15(3):219.
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Glycophorin A as a cell surface marker of early erythroid differentiation in acute leukemia.
Andersson LC, Gahmberg CG, Teerenhovi L, Vuopio P.
International Journal of Cancer 1979 Dec; 24(6):717.
Application:IF, IP, Human, Leukemic blasts, Erythrocytes.
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Glycophorin A expression in malignant hematopoiesis.
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