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c-Myc tag recombinant monoclonal antibody, clone 9E10

  • Catalog # : RAB00205
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  • Specification
  • Product Description:
  • Recombinant human monoclonal antibody raised against c-Myc tag.
  • Immunogen:
  • Original antibody is raised against a synthetic peptide corresponding to amino acids 408-439 at C-terminus of human c-Myc.
  • Reactivity:
  • Human
  • Specificity:
  • Epitope sequence is amino acids 410-419 of human c-myc protein (EQKLISEEDL).
  • Form:
  • Liquid
  • Purification:
  • Protein A affinity purification
  • Isotype:
  • IgG4, kappa
  • Recommend Usage:
  • Immunofluorescence
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% Proclin 300).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Antibody Species:
  • Human
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 4609
  • Gene Name:
  • MYC
  • Gene Alias:
  • bHLHe39,c-Myc
  • Gene Description:
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • Gene Summary:
  • The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq
  • Other Designations:
  • avian myelocytomatosis viral oncogene homolog,myc proto-oncogene protein,v-myc avian myelocytomatosis viral oncogene homolog
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