SHC1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SHC1.
Immunogen
A synthetic peptide corresponding to amino acids 450-474 of human SHC1 and mouse Shc1.
Sequence
LESSLPIVSAGSELCLQQPVERKP
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — SHC1
Entrez GeneID
6464Gene Name
SHC1
Gene Alias
FLJ26504, SHC, SHCA
Gene Description
SHC (Src homology 2 domain containing) transforming protein 1
Omim ID
600560Gene Ontology
HyperlinkOther Designations
OTTHUMP00000035409|OTTHUMP00000035471|SHC (Src homology 2 domain-containing) transforming protein 1|SHC-transforming protein 1
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Gene Info — Shc1
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Interactome
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Pathway
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Disease
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Publication Reference
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Combinatorial ShcA docking interactions support diversity in tissue morphogenesis.
Hardy WR, Li L, Wang Z, Sedy J, Fawcett J, Frank E, Kucera J, Pawson T.
Science 2007 Jul; 317(5835):251.
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A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
O'Bryan JP, Songyang Z, Cantley L, Der CJ, Pawson T.
PNAS 1996 Apr; 93(7):2729.
Application:WB-Ti, Mouse, Mouse brain.
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Combinatorial ShcA docking interactions support diversity in tissue morphogenesis.
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