GLIPR1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GLIPR1.
Immunogen
A synthetic peptide corresponding to human GLIPR1.
Sequence
C-NRQRDQVKRYYS
Host
Goat
Theoretical MW (kDa)
30.4
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — GLIPR1
Entrez GeneID
11010Protein Accession#
NP_006842.2Gene Name
GLIPR1
Gene Alias
CRISP7, GLIPR, RTVP1
Gene Description
GLI pathogenesis-related 1
Omim ID
602692Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
GLI pathogenesis-related 1 (glioma)|glioma pathogenesis-related protein 1|related to testis-specific, vespid, and pathogenesis proteins 1|testes-specific vespid and pathogenesis protein 1
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Interactome
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Disease
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Publication Reference
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RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer.
Ren C, Li L, Yang G, Timme TL, Goltsov A, Ren C, Ji X, Addai J, Luo H, Ittmann MM, Thompson TC.
Cancer Research 2004 Feb; 64(3):969.
Application:IHC-P, Human, Prostate.
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RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer.
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