GLIPR1 monoclonal antibody (M04), clone 8D9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GLIPR1.
Immunogen
GLIPR1 (NP_006842, 23 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGEN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (63)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.21 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GLIPR1 monoclonal antibody (M04), clone 8D9. Western Blot analysis of GLIPR1 expression in HeLa(Cat # L013V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GLIPR1 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — GLIPR1
Entrez GeneID
11010GeneBank Accession#
NM_006851Protein Accession#
NP_006842Gene Name
GLIPR1
Gene Alias
CRISP7, GLIPR, RTVP1
Gene Description
GLI pathogenesis-related 1
Omim ID
602692Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
GLI pathogenesis-related 1 (glioma)|glioma pathogenesis-related protein 1|related to testis-specific, vespid, and pathogenesis proteins 1|testes-specific vespid and pathogenesis protein 1
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Interactome
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Disease
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Publication Reference
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GliPR1 knockdown by RNA interference exerts anti-glioma effects in vitro and in vivo.
Urban J Scheuring, Steffi Ritter, Daniel Martin, Gabriele Schackert, Achim Temme, Stefanie Tietze.
Journal of Neuro-Oncology 2021 May; 153(1):23.
Application:WB-Tr, Human, A172, U87-MG, U343-MG cells.
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GliPR1 knockdown by RNA interference exerts anti-glioma effects in vitro and in vivo.
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