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Last updated: 2016/12/4
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GAB2 polyclonal antibody

  • Catalog # : PAB7265
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GAB2.
  • Immunogen:
  • A synthetic peptide corresponding to human GAB2.
  • Sequence:
  • C-QVDKEKTQALQN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 74.5, 70
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_536739.1, NP_0.36428.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.5-1.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • GAB2 polyclonal antibody (Cat # PAB7265) (0.5 ug/mL) staining of K-562 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9846
  • Protein Accession#:
  • NP_536739.1;NP_0.36428.1
  • Gene Name:
  • GAB2
  • Gene Alias:
  • KIAA0571
  • Gene Description:
  • GRB2-associated binding protein 2
  • Gene Summary:
  • This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • Grb2-associated binder 2
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