NOD2 polyclonal antibody (Cat # PAB7102) (0.1 ug/mL) staining of human peripheral blood mononucleocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
NLR family, CARD domain containing 2,NOD-like receptor C2,OTTHUMP00000164224,caspase recruitment domain family, member 15,caspase recruitment domain protein 15,inflammatory bowel disease protein 1,nucleotide-binding oligomerization domain 2,nucleotide-bin