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Last updated: 2016/12/4
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APBB1 polyclonal antibody

  • Catalog # : PAB7086
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of APBB1.
  • Immunogen:
  • A synthetic peptide corresponding to human APBB1.
  • Sequence:
  • C-GSLKPKRLGAHTP
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 77.2, 77
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_001155.1 and NP_663722.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • APBB1 polyclonal antibody (Cat # PAB7086) (0.1 ug/mL) staining of NIH/3T3 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 322
  • Protein Accession#:
  • NP_001155.1;NP_663722.1
  • Gene Name:
  • APBB1
  • Gene Alias:
  • FE65,MGC:9072,RIR
  • Gene Description:
  • amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • Gene Summary:
  • The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known. [provided by RefSeq
  • Other Designations:
  • adaptor protein FE65a2,amyloid beta A4 precursor protein-binding, family B, member 1,stat-like protein
  • Gene Pathway
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