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Last updated: 2016/12/4
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SCN5A polyclonal antibody

  • Catalog # : PAB6860
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SCN5A.
  • Immunogen:
  • A synthetic peptide corresponding to human SCN5A.
  • Sequence:
  • C-ETDDQSPEKIN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 227, 225, 223, 221
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_000326 and NP_932173).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6331
  • Protein Accession#:
  • NP_932173.1;NP_000326
  • Gene Name:
  • SCN5A
  • Gene Alias:
  • CDCD2,CMD1E,CMPD2,HB1,HB2,HBBD,HH1,ICCD,IVF,LQT3,Nav1.5,PFHB1,SSS1
  • Gene Description:
  • sodium channel, voltage-gated, type V, alpha subunit
  • Gene Summary:
  • The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • cardiac sodium channel alpha subunit,sodium channel, voltage-gated, type V, alpha (long QT syndrome 3),voltage-gated sodium channel type V alpha
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