SCN5A DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SCN5A DNA using DNAx™ Immune technology.
Technology
Immunogen
SCN5A (AAH51374.1, 1 a.a. ~ 223 a.a) full-length human DNA
Sequence
MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAASVLGTLFFPMSIQATSTS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SCN5A
Entrez GeneID
6331GeneBank Accession#
BC051374.1Protein Accession#
AAH51374.1Gene Name
SCN5A
Gene Alias
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1
Gene Description
sodium channel, voltage-gated, type V, alpha subunit
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
cardiac sodium channel alpha subunit|sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)|voltage-gated sodium channel type V alpha
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Interactome
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Disease
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