CPEB1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
CPEB1 polyclonal antibody (Cat # PAB6644) staining (0.5 ug/mL) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CPEB1.
Immunogen
A synthetic peptide corresponding to human CPEB1.
Sequence
C-PLMRNQKNRDSS
Host
Goat
Theoretical MW (kDa)
62.1, 54.2, 53.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CPEB1 polyclonal antibody (Cat # PAB6644) staining (0.5 ug/mL) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CPEB1
Entrez GeneID
64506Protein Accession#
NP_085097Gene Name
CPEB1
Gene Alias
CEBP, CPE-BP1, CPEB, FLJ13203, MGC34136, MGC60106
Gene Description
cytoplasmic polyadenylation element binding protein 1
Omim ID
607342Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CPE-binding protein 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein.
Welk JF, Charlesworth A, Smith GD, MacNicol AM.
Gene 2001 Jan; 263(1-2):113.
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Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein.
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