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Last updated: 2017/11/19

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RGS18 polyclonal antibody

  • Catalog # : PAB6634
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of RGS18.
  • Immunogen:
  • A synthetic peptide corresponding to human RGS18.
  • Sequence:
  • CNEFQDVQSDVAIWL
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 27.6
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • RGS18 polyclonal antibody (Cat # PAB6634, 1 ug/mL) staining of human peripheral blood mononucleocytes lysate (35 ug protein in RIPA buffer) . Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • RGS18
  • Gene Alias:
  • RGS13
  • Gene Description:
  • regulator of G-protein signaling 18
  • Gene Summary:
  • This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000033590,regulator of G-protein signalling 13,regulator of G-protein signalling 18
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