RGS18 MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of RGS18 expression in transfected 293T cell line (H00064407-T01) by RGS18 MaxPab polyclonal antibody.
Lane 1: RGS18 transfected lysate(25.96 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RGS18 protein.
Immunogen
RGS18 (AAH20632, 1 a.a. ~ 235 a.a) full-length human protein.
Sequence
METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RGS18 expression in transfected 293T cell line (H00064407-T01) by RGS18 MaxPab polyclonal antibody.
Lane 1: RGS18 transfected lysate(25.96 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RGS18
Entrez GeneID
64407GeneBank Accession#
BC020632Protein Accession#
AAH20632Gene Name
RGS18
Gene Alias
RGS13
Gene Description
regulator of G-protein signaling 18
Omim ID
607192Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
OTTHUMP00000033590|regulator of G-protein signalling 13|regulator of G-protein signalling 18
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Interactome
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Disease
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