OSBPL2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
OSBPL2 polyclonal antibody (Cat # PAB6514) staining (1.5 ug/mL) of human heart lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of OSBPL2.
Immunogen
A synthetic peptide corresponding to C-terminus of human OSBPL2.
Sequence
YFERNFSDCPDIY
Host
Goat
Theoretical MW (kDa)
54, 55.2
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (represented by NP_055650.1 and NP_653081.1)
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:8000)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
OSBPL2 polyclonal antibody (Cat # PAB6514) staining (1.5 ug/mL) of human heart lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — OSBPL2
Entrez GeneID
9885Protein Accession#
NP_055650.1;NP_653081.1Gene Name
OSBPL2
Gene Alias
FLJ20223, KIAA0772, MGC4307, MGC8342, ORP-2, ORP2
Gene Description
oxysterol binding protein-like 2
Omim ID
606731Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
OSBP-related protein 2|OTTHUMP00000031478|OTTHUMP00000031479|oxysterol-binding protein-like 2|oxysterol-binding protein-like protein 2|oxysterol-binding protein-related protein 2
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Interactome
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Disease
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Publication Reference
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The OSBP-related protein family in humans.
Lehto M, Laitinen S, Chinetti G, Johansson M, Ehnholm C, Staels B, Ikonen E, Olkkonen VM.
Journal of Lipid Research 2001 Aug; 42(8):1203.
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The OSBP-related protein family in humans.
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