Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

OSBPL2

Gene Alias

FLJ20223, KIAA0772, MGC4307, MGC8342, ORP-2, ORP2

Gene Description

oxysterol binding protein-like 2

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq

Other Designations

OSBP-related protein 2|OTTHUMP00000031478|OTTHUMP00000031479|oxysterol-binding protein-like 2|oxysterol-binding protein-like protein 2|oxysterol-binding protein-related protein 2