ACSL4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
ACSL4 polyclonal antibody (Cat # PAB6260) (0.1 ug/mL) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ACSL4.
Immunogen
A synthetic peptide corresponding to human ACSL4.
Sequence
C-HYLKDIERMYGGK
Host
Goat
Theoretical MW (kDa)
74.4, 79.2
Reactivity
Human
Specificity
This antibody is expected to recognize both reported human isoforms, as represented by NP_004449 and NP_075266.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
ACSL4 polyclonal antibody (Cat # PAB6260) (0.1 ug/mL) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ACSL4
Entrez GeneID
2182Protein Accession#
NP_004449;NP_075266Gene Name
ACSL4
Gene Alias
ACS4, FACL4, LACS4, MRX63, MRX68
Gene Description
acyl-CoA synthetase long-chain family member 4
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000023846|acyl-CoA synthetase 4|fatty-acid-Coenzyme A ligase, long-chain 4|lignoceroyl-CoA synthase|long-chain fatty-acid-Coenzyme A ligase 4
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Interactome
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Pathway
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Disease
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Publication Reference
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FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation.
Piccini M, Vitelli F, Bruttini M, Pober BR, Jonsson JJ, Villanova M, Zollo M, Borsani G, Ballabio A, Renieri A.
Genomics 1998 Feb; 47(3):350.
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FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation.
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