NFATC4 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
NFATC4 polyclonal antibody (Cat # PAB6219) (3.8 ug/mL) staining of paraffin embedded human placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NFATC4.
Immunogen
A synthetic peptide corresponding to C terminus of human NFATC4.
Sequence
C-SGFPAPPGEEPPA
Host
Goat
Theoretical MW (kDa)
104
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-3.8 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
NFATC4 polyclonal antibody (Cat # PAB6219) (3.8 ug/mL) staining of paraffin embedded human placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NFATC4
Entrez GeneID
4776Protein Accession#
NP_004545Gene Name
NFATC4
Gene Alias
NF-ATc4, NFAT3
Gene Description
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
Omim ID
602699Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
T cell transcription factor NFAT3|nuclear factor of activated T-cells, cytoplasmic 4
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Interactome
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Pathway
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Disease
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Publication Reference
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Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins.
Hoey T, Sun YL, Williamson K, Xu X.
Immunity 1995 May; 2(5):461.
Application：WB-Ti, Human, Lungs, Kidneys, Lungs, Placenta, Testes, Ovaries.
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Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins.
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